Fistulas as a complication of cervical cancer: the current state of the problem
https://doi.org/10.17650/2686-9594-2023-13-1-39-44
Abstract
One of the possible adverse events of cervical cancer arising both as a result of the progression of the disease and as a result of the treatment, leading to a significant decrease in the quality of life, is the development of genital fistulas. This review presents current information on diagnostic approaches, and treatment options for fistulas caused by cervical cancer. The peculiarities of fistulas that have arisen after radiation therapy and surgical treatment are highlighted.
About the Authors
M. N. Saryev
A. S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department
Russian Federation
Russian Federation
Mukhammetsakhet Nurberdievich Saryev
86 Shosse Entuziastov, Moscow 111123
M. B. Nurberdyev
A. S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department
Russian Federation
Russian Federation
86 Shosse Entuziastov, Moscow 111123
R. K. Valiev
A. S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department
Russian Federation
Russian Federation
86 Shosse Entuziastov, Moscow 111123
M. I. Nechushkin
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
E. A. Tizilova
A. S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department
Russian Federation
Russian Federation
86 Shosse Entuziastov, Moscow 111123
A. S. Tikhomirova
National Medical and Surgical Center named after N. I. Pirogov, Ministry of Health of Russia
Russian Federation
Russian Federation
70 Nizhnyaya Pervomayskaya St., Moscow 105203
V. A. Aliev
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
References
1. Virdee N.K., Ringdal E.K., Thornhill H. et al. Gynaecological fistulae after surgery or radiotherapy. Gynekologiske fistler etter kirurgi eller strålebehandling. Tidsskr Nor Laegeforen 2020;140(12):10.4045/tidsskr.19.0822. DOI: 10.4045/tidsskr.19.0822
2. Smirnova T.A., Novodvorskaya O.D. Genital fistulas in the practice of obstetrician-gynecologist. Medicinskij zhurnal = Medical Journal 2016;2(56):145–8. (In Russ.).
3. Paspulati R.M., Dalal T.A. Imaging of complications following gynecologic surgery. Radiographics 2010;30(3):625–42. DOI: 10.1148/rg.303095129
4. Rogers R.G., Jeppson P.C. Current Diagnosis and Management of Pelvic Fistulae in Women. Obstet Gynecol 2016;128(3):635–50. DOI: 10.1097/AOG.0000000000001519
5. Chen I.E., Ferraro R., Chow L., Bahrami S. Guided tour of hidden tracts in the pelvis: exploring pelvic fistulas. Arch Gynecol Obstet 2021;304(4):863–71. DOI: 10.1007/s00404-021-06144-1
6. Aarts J.W., Nieboer T.E., Johnson N. et al. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database Syst Rev 2015;2015(8):CD003677. DOI: 10.1002/14651858.CD003677.pub5
7. Allanson E.R., Powell A., Bulsara M. et al. Morbidity after surgical management of cervical cancer in low and middle income countries: A systematic review and meta-analysis. PLoS One 2019;14(7):e0217775. DOI: 10.1371/journal.pone.0217775
8. Hillary C.J., Osman N.I., Hilton P., Chapple C.R. The Aetiology, treatment, and outcome of urogenital fistulae managed in well- and low-resourced countries: a systematic review. Eur Urol 2016;70(3):478–92. DOI: 10.1016/j.eururo.2016.02.015
9. Avritscher R., Madoff D.C., Ramirez P.T. et al. Fistulas of the lower urinary tract: percutaneous approaches for the management of a difficult clinical entity. Radiographics 2004;24(Suppl 1):217–36. DOI: 10.1148/rg.24si045508
10. Papadopoulou I., Stewart V., Barwick T.D. et al. Post-radiation therapy imaging appearances in cervical carcinoma. Radiographics 2016;36(2):538–53. DOI: 10.1148/rg.2016150117
11. Debas H.T., Donkor P., Gawande A. et al. Essential Surgery: Disease Control Priorities, Third Edition (Volume 1). Washington (DC): The International Bank for Reconstruction and Development/The World Bank, 2015.
12. Viswanathan A.N., Lee L.J., Eswara J.R. et al. Complications of pelvic radiation in patients treated for gynecologic malignancies. Cancer 2014;120(24):3870–83. DOI: 10.1002/cncr.28849
13. Welk B., Wallis C., D’Souza D. et al. A population-based assessment of urologic procedures and operations after surgery or pelvic radiation for cervical cancer. Int J Gynecol Cancer 2018;28(5):989–95. DOI: 10.1097/IGC.0000000000001266
14. Palavalli Parsons L.H., Roane B., Manders D.B. et al. Hypoalbuminemia is a predictive factor for fistula formation in recurrent cervical cancer. Am J Clin Oncol 2018;41(10):933–7. DOI: 10.1097/COC.0000000000000403
15. Eliseev D.E., Alekseev B.Ya., Kachmazov A.A. et al. Optimization of diagnostics of genitourinary and intestinal-vaginal fistulas. Eksperimental’naya i klinicheskaya urologiya = Experimental and clinical urology 2017;4:82–8. (In Russ.).
16. Tonolini M., Bianco R. Multidetector CT cystography for imaging colovesical fistulas and iatrogenic bladder leaks. Insights Imaging 2012;3(2):181–7. DOI: 10.1007/s13244-011-0145-9
17. Healy J.C., Phillips R.R., Reznek R.H. et al. The MR appearance of vaginal fistulas. AJR Am J Roentgenol 1996;167(6):1487–9. DOI: 10.2214/ajr.167.6.8956582
18. Stamatakos M., Sargedi K., Ntzeros K. et al. Aetiology, evaluation and management of rectovaginal fistula: A rare entity and a major surgical challenge. Hellenic J Surg 2014;86:72–82. DOI: 10.1007/s13126-014-0101-5
19. Lee J.K., Stein S.L. Radiographic and endoscopic diagnosis and treatment of enterocutaneous fistulas. Clin Colon Rectal Surg 2010;23:149–60. DOI: 10.1055/s-0030-1262982
20. Van Buren W.M., Lightner A.L., Kim S.T. et al. Imaging and surgical management of anorectal vaginal fistulas. Radiographics 2018;38(5):1385–401. DOI: 10.1148/rg.2018170167
21. Mohr S., Brandner S., Mueller M.D. et al. Sexual function after vaginal and abdominal fistula repair. Am J Obstet Gynecol 2014;211(1):74.e1–6. DOI: 10.1016/j.ajog.2014.02.011
22. Stovsky M.D., Ignatoff J.M., Blum M.D. et al. Use of electrocoagulation in the treatment of vesicovaginal fistulas. J Urol 1994;152:1443–4. DOI: 10.1016/s0022-5347(17)32441-2
23. Shah S.J. Role of day care vesicovaginal fistula fulguration in small vesicovaginal fistula. J Endourol 2010;24(10):1659–60. DOI: 10.1089/end.2009.0557
24. Walters M.D., Karram M.M. Urogynecology and reconstructive pelvic surgery. 3rd ed. Philadelphia (PA): Mosby, 2007.
25. Clinical recommendations. Coloproctology. Rectovaginal fistulas. Ed. by Yu.A. Shelygin. Moscow: GEOTAR-Media, 2015. (In Russ.).
26. Eliseev D.E., Eliseev E.N., Aimamedova O.N. et al. Surgical treatment of rectovaginal fistulas. The experience of plastic surgery of the radial rectovaginal fistula with a flap of Martius–Symmonds. Onkoginekologiya = Oncogynecology 2015;2:59–69.
27. Symmonds R.E., Hill L.M. Loss of the urethra: a report on 50 patients. Am J Obstet Gynecol 1978;130:130–8.
28. Kniery K.R., Johnson E.K., Steele S.R. Operative considerations for rectovaginal fistulas. World J Gastrointest Surg 2015;7(8):133–7. DOI: 10.4240/wjgs.v7.i8.133
29. Papadopoulos O., Konofaos P., Georgiou P. et al. Gracilis myocutaneous flap: evaluation of potential risk factors and long-term donor-site morbidity. Microsurgery 2011;31(6):448–53. DOI: 10.1002/micr.20899
30. Medvedev V.L., Opolskiy A.M. Optimization of surgical treatment of vesicovaginal fistulas. Vestnik urologii = Herald Urology 2017;5(3):79–86. (In Russ.). DOI: 10.21886/2306-6424-2017-5-3-79-86
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