Pancreatic leiomyosarcoma: a case report
M. P. Nikulin,
V. V. Yugay,
N. A. Kozlov,
P. P. Arkhiri,
M. M. Gabrava,
S. S. Magamedova,
I. S. Stilidi https://doi.org/10.17650/2686-9594-2021-11-3-4-40-45
Abstract
Primary pancreatic leiomyosarcoma belongs to a rare group of malignant soft tissue tumors. we present a clinical case of a 61-year-old patient who underwent hemipancreatectomy with splenectomy for a pancreatic tumor in 2018. Histological and immunohistochemical studies confirmed the diagnosis of leiomyosarcoma. for three years, the patient has been observed at the N.N. Blokhin National Medical Research Center of Oncology of ministry of Health of Russia without signs of progression.
About the Authors
M. P. Nikulin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Oncology, Faculty of Postgraduate Education
23 Kashirskoe Shosse, Moscow 115478
20/1 Delegatskaya St., Moscow 127473
V. V. Yugay
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Vladimir Viktorovich Yugay
23 Kashirskoe Shosse, Moscow 115478
N. A. Kozlov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
P. P. Arkhiri
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia
Russian Federation
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
2/1 Barrikadnaya St., Moscow 125993
M. M. Gabrava
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
S. S. Magamedova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
I. S. Stilidi
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
1 Ostrovityanova St., Moscow 117997
References
1. Weiss S.W., Goldblum J.R. Leiomyosarcoma. In: Enzinger and Weiss’s Soft Tissue Tumors. 4th edn. Mosby, St. Louis, 2001.
2. Rajiah P., Sinha R., Cuevas C. Imaging of uncommon retroperitoneal masses. RadioGraphics 2011;31(4):949–76. DOI: 10.1148/rg.314095132.
3. Baylor S.M., Berg J.W. Cross classification and survival characteristics of 5000 cases of cancer of the pancreas. J Surg Oncol 1973;5:335–58. DOI: 10.1002/jso.2930050410.
4. Ross C. Leiomyosarcoma of the pancreas. Brit J Surg 1951;39(153):53–6. DOI: 10.1002/bjs.18003915311.
5. Aleshawi A., Allouh, M., Heis F. et al. Primary leiomyosarcoma of the pancreas: a comprehensive analytical review. J Gastrointest Cancer 2019;51(2):433–38. DOI: 10.1007/s12029-019-00282-1.
6. Riddle N., Quigley B., Browarsky I., Bui M. Leiomyosarcoma arising in the pancreatic duct: a case report and review of the current literature. Case Rep Med 2010:1–4. DOI: 10.1155/2010/252364.
7. Patrono D., Molinaro L., Mazza E. et al. Splenic vein leiomyosarcoma: case report and review of the literature. JOP 2014;15(5):512–4. DOI: 10.6092/1590-8577/2803.
8. Лагкуева И.Д., Ребрикова В.А., Егорова Е.В. и др. Компьютерно-томографическая семиотика лейомиосаркомы забрюшинной локализации, исходящей из мышечной стенки селезеночной вены (клиническое наблюдение). Сибирский онкологический журнал 2019;17(6):123–7. [Lagkueva I., Rebrikova V., Egorova E. et al. Computer tomographic semiotics of retroperitoneal leiomyosarcoma arising from the muscular wall of the splenic vein: a case report. Sibirskiy onkologicheskiy zhurnal = Siberian journal of oncology 2019;17(6):123–7. (In Russ.)]. DOI: 10.21294/1814-4861-2018-17-6-123-127.
9. Akhaladze G., Grebenkin E., Goncharov S. et al. Leiomyosarcoma of the splenic vein. Khirurgiya. Zhurnal im. N.I. Pirogova 2019;(10):82. DOI: 10.17116/hirurgia201910182.
10. Nordback I., Mattila J., Tarkka M. Resectable leiomyosarcoma of inferior vena cava presenting as carcinoma of the pancreas. Case report. Acta Chir Scand 1990;156:577–80.
11. Xu J., Zhang T., Wang T. et al. Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review. World J Surg Oncol 2013;11(1):290. DOI: 10.1186/1477-7819-11-290.
12. Russ P.D. Leiomyosarcoma of the pancreatic bed detected on CT scans. AJR Am J Roentgenol 1993;161(1):210. DOI: 10.2214/ajr.161.1.8517309.
13. Diz Rodriguez M.R., Virseda Chamorro M., Ramirez Garcia J.R. et al. Scrotal leiomyosarcoma with bone metastasis. Acta Urol Esp 2006;30(6):638–40. DOI: 10.1016/s0210-4806(06)73507-0.
14. Tilkorn D.J., Lehnhardt M., Hauser J. et al. Intravascular leiomyosarcoma of the brachiocephalic region – report of an unusual tumour localisation: case report and review of the literature. World J Surg Oncol 2008;6:113. DOI: 10.1186/1477-7819-6-113.
15. Miura F., Takada T., Amano H. et al. Diagnosis of pancreatic cancer. HPB (Oxford) 2006;8(5):337–42. 16. O’Sullivan P.J., Harris A.C., Munk P.L. Radiological imaging features of nonuterine leiomyosarcoma. Br J Radiol 2008;81(961):73–81. DOI: 10.1259/bjr/18595145.
16. Burke A.P., Virmani R., Sarcomas of the great vessels. A clinicopathologic study. Cancer 1993;71(5):1761–73. DOI: 10.1002/1097-0142(19930301)71: 5<1761::help-cncr2820710510>3.0.co;2-7.
17. Maarouf A., Scoazec J., Berger F., Partensky C. Cystic leiomyosarcoma of the pancreas successfully treated by splenopancreatectomy. A 20-year follow-up. Pancreas 2007;35:95–7. DOI: 10.1097/01.mpa.0000278689.86306.70.
18. DeAlva E., Tarramade J., Vazquez J., Leiomyosarcoma of the pancreas. Virchows Arch 1993;422:419–22. DOI: 10.1007/BF01605462.
19. Lakhoo K., Maunell A. Pancreatic leiomyosarcoma: a case report. S Afr J Surg 1991;29(2):59–60.
20. Hollenbeck S.T., Grobmyer S.R., Kent K.C., Brennan M.F. Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma. J Am Coll Surg 2003;197:575–9. DOI: 10.1016/S1072-7515(03)00433-2.
21. Makimoto S., Hatano K., Kataoka N. et al. A case report of primary pancreatic leiomyosarcoma requiring six additional resections for recurrences. Int J Surg Case Rep 2017;41:272–6. DOI: 10.1016/j.ijscr.2017.10.039.
22. Group ESESNW. Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2014;25(Suppl 3):iii102–12.
23. Hines O.J., Nelson S., QuinonesBaldrich W.J., Eilber F.R. Leiomyosarcoma of the inferior vena cava: Prognosis and comparison with leiomyosarcoma of other anatomic sites. Cancer 1999;l85:1077–83.
24. Casali P., Abecassis N., Bauer S. et al. Soft tissue and visceral sarcomas: ESMO– EURACAN clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2018;29. DOI: 10.1093/annonc/mdy321.
25. Hollenbeck S.T., Grobmyer S.R., Kent K.C., Brennan M.F. Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma. J Am Coll Surg 2003;197:575–9. DOI: 10.1016/S1072-7515(03)00433-2.
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