A RARE CASE OF TREATMENT POLICY FOR RECURRENT NEUROENDOCRINE CARCINOMA OF THE ANAL CANAL
https://doi.org/10.17650/2220-3478-2012-0-1-31-34
Abstract
A rare case of multicomponental treatment of low-differentiated anal neuroendocrine cancer is presented. By using combined treatment involving chemotherapy, local hyperthermia and radiotherapy a complete response of recurrent neuroendocrine cancer has been achieved.
A review of modern methods of diagnostics and treatment of rectal neurtoendocrine tumors is presented and possibilities of modern combined treatment are discussed.
About the Authors
Y. A. Barsukov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
D. F. Kim
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
S. I. Guturov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
S. S. Gordeyev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
References
1. Rosenberg J.L., Welch J.P. Carcinoid tumors of the colon. Ann J Surg 1985;149(6):775–9.
2. Барсуков Ю.А., Алиев В.А., Перевощиков А.Г., Кузьмичев Д.В., Мазуров С.Т., Крупноклеточный нейроэндокринный рак прямой кишки. Случай из практики. Вестник РОНЦ им. Н.Н. Блохина РАМН 2009;2(20):52–7.
3. Кныш В.И., Тимофеев Ю.М., Тимофеев Н.Н., Перевощиков А.Г. Карциноид прямой кишки. Вопр онкол 1990;36(6):675–8.
4. Kaltsas G.A., Besser G.M., Grossman A.B. The diagnosis and medical management of advanced neuroendocrine tumors. Endocr Rev 2004;25(3):458–511.
5. Kulke M.H., Siu L.L. et al. Future directions in the treatment of neuroendocrine tumors: consensus report of the National Cancer Institute Neuroendocrine Tumor clinical trials planning meeting. J Clin Oncol 2011;29(7):934–43.
6. Klimstra D.S., Modlin I.R. et al. The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems. Pancreas 2010 Aug;39(6):707–12.
7. Ramage J.K., Goretzki P.E., Manfredi R. et al. Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated colon and rectum tumour/carcinoma. Neuroendocrinology 2008;87(1):31–9. doi: 10.1159/000111036 November 21, 2007
8. Ramage J.K., Davies A.H., Ardill J. et al. On behalf of UKNET work for neuroendocrine tumours. Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours. Gut 2005;54(Suppl IV):iv1–16. doi: 10.1136/gut.2004.053314
9. Modlin I.M., Sandor A. An analysis of 8305 cases of carcinoid tumors. Cancer 1997;79:813–29.
10. Modlin I.M., Lye K.D., Kidd M. A five-decade analysis of 13,715 carcinoid tumors. Cancer 2003;97:934–59.
11. Ahlman H., Nilsson O., McNicol A.M. Poorly-differentiated endocrine carcinomas of midgut and hindgut origin. Neuroendocrinology 2008;87:40–6. doi: 10.1159/000109976 October 16, 2007
12. Chang S., Choi D. et al. Neuroendocrine neoplasms of the gastrointestinal tract: classification, pathologic basis, and imaging features. Radiographics 2007;27(6):1667–79.
13. Williams E.D., Sandler M. The classification of carcinoid tumours. Lancet 1963;1:238–9.
14. Rindi G., Klöppel G., Alhman H. et al. TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2006; 449:395–401.
15. Rindi G., Klöppel G., Couvelard A. et al. TNM staging of midgut and hindgut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2007;451:757–62.
16. Гуторов С.Л. Некоторые аспекты клиники и лечения карциноида. Трудный пациент 2006;11:23.
17. Mani S., Modlin I.M., Ballantyne G. et al. Carcinoids of the rectum. J Am Coll Surg 1994;179(2):231–48.
18. Klöppel G., Perren A., Heitz P.U. The gastroenteropancreatic neuroendocrine cell system and its tumors: the WHO classification. Ann N Y Acad Sci 2004; 1014:13–27.
19. Kobayashi K., Katsumata T., Yoshizawa S. et al. Indications of endoscopic polypectomy for rectal carcinoid tumors and clinical usefulness of endoscopic ultrasonography. Dis Colon Rectum 2005;48(2):285–91.
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