COMBINED USE OF ENDOSCOPIC TECHNIQUES IN THE DIAGNOSIS OF EARLY COLONIC CANCER
https://doi.org/10.17650/2220-3478-2013-0-2-42-47
Abstract
The aim of the research: explore the possibilities of modern visual differential diagnostics of early colon cancer and bening colon tumors.
Methods.Results of endoscopic examination of 174 patients with unclear endoscopic data were analyzed. These patients underwent complex diagnostics, which revealed 293 tumors. Following groups were distinguished (according to the results of morphological study of biomaterial and visual endoscopic evaluation): early colon cancer – 28, lobular hyperplasia of the mucous shell – 38, polyps (adenomas with dysplasia varying degrees) – 184, limited infiltrative cancer – 37, neuroendocrine tumors – 6.
Results.Visual and morphological data coincided in 89.3 % patients, sensitivity 93.9 %, specificity of 88.6 %, positive predictive value 90.4 %, negative predictive value 82.4 %, accuracy of 89.6 %.
Conclusions. Use of the complex endoscopic diagnostics allows to identify the neoplastic changes of the mucous membrane in the early stages of development, and make a high-precision biopsy.
About the Authors
I. A. Karasyov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
I. B. Perfilyev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
S. T. Mazurov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
B. K. Poddubny
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
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